Search results for "Time path"
showing 3 items of 3 documents
Composite Scaffolds with a Hydrohyapatite Spatial Gradient for Osteochondral Defect Repair
2018
Osteochondral defects derived by traumatic injury or aging related disease are often associated with severe joint pain and progressive loss of joint functions for millions of people worldwide and represent a major challenge for the orthopedic community. Tissue engineering offers new therapeutic approach to repair the osteochondral defects, through the production of scaffolds manufactured to mimic their complex architecture, which consists of cartilage and bone layers. Composite scaffolds based on a PLLA polymeric matrix containing hydroxyapatite (HA) as a filler were prepared through a modified thermally induced phase separation (TIPS) protocol. A suspension was prepared by adding sieved HA…
Innovation Dynamics in Space: Local Actors and Local Factors
1997
This paper addresses the issue of technogenesis and its geographical pattern. It aims to offer both a general analysis framework and a test on innovation data from several European cities. This framework is mainly built on the product life-cycle and the incubation approach. On the basis of this framework, it is argued that the phases of an industrial life-cycle have several firm-specific effects. First, these phases influence innovativeness and thus profit levels, output and employment of firms in a spatially distinct way. Second, the phases of the life-cycle mirror the importance of local factors for innovations, and third, they affect strategic decisions of firms, inter alia by influencin…
Bubbles and Crowding-in of Capital via a Savings Glut
2017
This paper uncovers a mechanism by which bubbles crowd in capital investment. If capital formation is initially depressed by a binding credit constraint, a bubble triggers a savings glut. Higher returns in a new bubbly equilibrium attract additional savings, which are channeled to expand investment at the extensive margin, leading to permanently higher capital, output, and wages. We demonstrate that crowding-in through this channel is a robust phenomenon that occurs along the entire time path.